Thursday, April 5, 2012

The description of Acepromazine maleate


 The standard pharmaceutical preparation, acepromazine maleate, is used in veterinary medicine in dogs, and cats. Its use in horses has fallen out of favor due to the risk of paraphimosis and persistent priapism in stallions. Its potential for cardiac effects, namely hypotension, can be profound and as such is not recommended for use in geriatric or debilitated animals, especially dogs. In these cases it is most often substituted with midazolam or diazepam and left out of the preanesthetic medication altogether.
Acepromazine Maleate Tablets 5, 10, & 25 mg in bottles of 100 and 500 tablets; PromAce ® (Fort Dodge); generic; (Rx). Approved for use in dogs, cats and horses not intended for food.Acepromazine Maleate for Injection 10 mg/ml for injection in 50 ml vials;PromAce® (Fort Dodge); generic; (Rx). Approved for use in dogs, cats and horses not intended for food.

Acepromazine Maleate Tablets 5, 10, & 25 mg in bottles of 100 and 500 tablets; PromAce ® (Fort Dodge); generic; (Rx). Approved for use in dogs, cats and horses not intended for food.Acepromazine is a phenothiazine neuroleptic agent. While the exact mechanisms of action are not fully understood, the phenothiazines block postsynaptic dopamine receptors in the CNS and may also inhibit the release of, and increase the turnover rate of dopamine. They are thought to depress portions of the reticular activating system which assists in the control of body temperature, basal metabolic rate, emesis, vasomotor tone, hormonal balance, and alertness. Additionally, phenothiazines have varying degrees of anticholinergic, antihistaminic, antispasmodic, and alpha-adrenergic blocking effects.
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