Information about Ceftazidime

Ceftazidime is usually reserved for the treatment of infections caused by Pseudomonas aeruginosa. It is also used in the empirical therapy of febrile neutropenia, in combination with other antibiotics. It is usually given IV or IM every 8–12 hours (2 - 3 times a day), with dosage varying by the indication, infection severity, and/or renal function of the recipient.
Ceftazidine is first line treatment for the rare tropical infection, melioidosis.
In addition to the syn-configuration of the imino side chain, compared to other third-generation cephalosporins, the more complex moiety (containing two methyl and a carboxylic acid group) confers extra stability to β-lactamase enzymes produced by many Gram-negative bacteria. The extra stability to β-lactamases increases the activity of ceftazidime against otherwise resistant Gram-negative organisms including Pseudomonas aeruginosa. The charged pyridinium moiety increases water-solubility.

the description of Chymotrypsin

Chymotrypsin is a proteolytic enzyme,which preferentially catalyzes the hydrolysis of peptide bonds involving L-isomers of tyrosine, phenylalanine and tryptophan.The optimum pH is 8.0.The enzyme is inhibited by heavy metals, the natural trypsin inhibitors to various degrees.It is the zymogen form of chymotrypsin. It belongs to the molecular class of serine protease. The molecular weight of Chymotrypsinogen is 25000 Da.Chymotrypsinogen is purified by several crystallization stages, and shows a single band on SDS-PAGE.
Chymotrypsin is synthesized in the pancreas by protein biosynthesis as a precursor called chymotrypsinogen that is enzymatically inactive. On cleavage by trypsin into two parts that are still connected via an S-S bond, cleaved chymotrypsinogen molecules can activate each other by removing two small peptides in a trans-proteolysis. The resulting molecule is active chymotrypsin, a three-polypeptide molecule interconnected via disulfide bonds.
CAS:9004-07-3
Source:Bovine Pancreas
Storage:Preserve in tight containers,and avoid exposure to excessive heat.

the use of Mupirocin

Mupirocin is an antibiotic cream/ointment which you apply to your skin to treat skin infections. It is used in particular to treat infections caused by meticillin-resistant Staphylococcus aureus (MRSA). It works by killing the bacteria causing the infection. 
Mupirocin, an antibiotic, is used to treat impetigo as well as other skin infections caused by bacteria. It is not effective against fungal or viral infections.This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information.
Mupirocin comes in an ointment that is applied to the skin. Mupirocin usually is applied three times a day for 1 to 2 weeks. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Use mupirocin exactly as directed. Do not use more or less of it or use it more often than prescribed by your doctor.Wash the affected skin area thoroughly, and then gently apply a small amount (a thin film) of the ointment. You may cover the area with a sterile gauze dressing.
CAS : 12650-69-0
Molecular Formula : C26H44O9
Formula Weight : 500.62

the use of Desloratadine

Desloratadine is a drug used to treat allergies. It is marketed under several trade names such as NeoClarityn, Claramax, Clarinex, Larinex, Aerius, Dazit, Azomyr, Deselex and Delot. It is an active metabolite of loratadine, which is also on the market. It has a long-lasting effect and does not cause drowsiness because it does not readily enter the central nervous system.
Desloratadine is  used to treat allergies. Desloratadine is a tricyclic antihistamine, which has a selective and peripheral H1-antagonist action. It is an antagonist at histamine H1 receptors, and an antagonist at all subtypes of the muscarinic acetylcholine receptor. It has a long-lasting effect and in moderate and low doses, does not cause drowsiness because it does not readily enter the central nervous system. Unlike other antihistamines, desloratadine is also effective in relieving nasal congestion, particularly in patients with allergic rhinitis.
Desloratadine is a tricyclic antihistamine, which has a selective and peripheral H1-antagonist action. It is an antagonist at histamine H1 receptors, and an antagonist at all subtypes of the muscarinic acetylcholine receptor. It has a long-lasting effect and in moderate and low doses, does not cause drowsiness because it does not readily enter the central nervous system. Unlike other antihistamines, desloratadine is also effective in relieving nasal congestion, particularly in patients with allergic rhinitis. 
CAS:100643-71-8
Molecular Formula:C19H19ClN2
Molecular Weight:310.82

About Shark Cartilage

Shark Cartilage is a premium dietary supplement that provides active cartilage protein for cellular protection. Using no radiation or ethylene oxide.Shark Cartilage Powder is rich in minerals and amino acids.Processing selectively removes unwanted tissue to retain more of the protein-rich soft cartilage that other processing methods may destroy.Each 6-gram scoop provides approximately 3 grams active cartilage protein.
Proponents of shark cartilage are encouraged by anecdotal evidence from users as to its efficacy. The proponents also cite studies that show that shark cartilage has had some success in preventing angiogenesis, the growth of new blood vessels from pre-existing vessels. While angiogenesis is often a normal function, it is also consistent with the growth of malignant tumors. They argue too, that very little research (in the quantity and quality of studies) has been conducted, and thus the benefits cannot be scientifically disputed.
Opponents cite existing studies of shark cartilage on a variety of cancers that produced negligible to non-existent results in the prevention or treatment of cancer. Most notable among these was a breast-cancer trial conducted by the Mayo Clinic that stated that the trial "was unable to demonstrate any suggestion of efficacy for this shark cartilage product in patients with advanced cancer." The results of another clinical trial were presented at the 43rd annual meeting of the American Society for Clinical Oncology. In that study (sponsored by the National Cancer Institute), "researchers did not find a statistical difference in survival" between patients receiving shark cartilage and those taking a placebo. Scientific evidence does not support the efficacy of Shark Cartilage nor the ability of effective components to remove cancer cells. The fact that people believe eating shark cartilage can cure cancer shows the serious potential impacts of pseudoscience.

Detail information about GHRP-2 Acetate

CAS No. 158861-67-7
Molecular Formula C45H55N9O6
Molecular Weight 817.97
Storage 2～8℃
Batch No. 20071220
Manufacturing Date 2007-12-21
Retest Date 2007-12-21
Sequence D-Ala-D-β-Nal-Ala-Trp-D-Phe-Lys-NH2

1	Assay	95.0～105.0%	97.0%
2	Appearance	White powder	White powder
3	Solubility	Soluble in water or acetic acid to give a clear, colorless solution	Conforms
4	Amino Acid Composition	±10% of theoretical	Conforms
5	Peptide Purity (By HPLC)	>95.0% by area integration	97.0%
6	Related Substance(By HPLC)	Total Impurities(%) <5.0% Largest Single Impurity(%)<1.0%	3.0% 0.5%
7	Acetate Content (By HPLC)	<15.0%	13.5%
8	Water Content (Karl Fischer)	<8.0%	2.0%
9	Bacterial Endotoxins	<5EU/mg	Conform
10	Peptide Content(By N determination)	>80.0%	83.8%

More about  GHRP-2 Acetate

About (R)-(-)-MANDELIC ACID

Mandelic acid is an aromatic alpha hydroxy acid with the molecular formula C6H5CH(OH)CO2H. It is a white crystalline solid that is soluble in water and polar organic solvents. It is a useful precursor to various drugs. Since the molecule is chiral, it exists in either of two enantiomers as well as the racemic mixture, known as paramandelic acid.
Mandelic acid has a long history of use in the medical community as an antibacterial, particularly in the treatment of urinary tract infections. It has also been used as an oral antibiotic, and as a component of 'chemical face peels', along with other alpha-hydroxy acids (AHAs).
The drugs cyclandelate and homatropine are esters of mandelic acid.

Product name:(R)-(-)-Mandelic acid
CAS:611-71-2
Molecular formula:C8H8O3
Molecular weight:152.15

what is the Methylcobalamin ?

Methylcobalamin is the form of vitamin B12 active in the central nervous system. It is an active coenzyme of the vitamin B12 analogs, that is essential for cell growth and replication. The liver may not convert cyanocobalamin, the common supplemental form of vitamin B12, into adequate amounts of methylcobalamin the body may need for proper neuronal functioning. Methylcobalamin may exert its neuroprotective effects through enhanced methylation, acceleration of nerve cell growth, or its ability to promote healthy homocysteine levels. For methylcobalamin to be available to the brain, it should be allowed to dissolve under the tongue.

This vitamer is one of two active coenzymes used by vitamin B12-dependent enzymes and is the specific vitamin B12 form used by 5-methyltetrahydrofolate-homocysteine methyltransferase (MTR), also known as methionine synthase.
Methylcobalamin participates in the Wood-Ljungdahl pathway, which is a pathway by which some organisms utilize carbon dioxide as their source of organic compounds. In this pathway, methylcobalamin provides the methyl group that couples to carbon monoxide (derived from CO2) to afford acetyl-CoA. Acetyl-CoA is a derivative of acetic acid that is converted to more complex molecules as required by the organism.
Methylcobalamin is produced by some bacteria. It plays an important role in the environment. In the environment, it is responsible for the biomethylation of certain heavy metals. 

The use of Sucralfate

Sucralfate is an anti-ulcer drug useful for the treatment and prevention of gastric (stomach) and intestinal ulcers.Sucralfate is used in the treatment and prevention of oral (mouth), esophagus (food tube), stomach and intestinal ulcers. Sucralfate promotes healing in animals with ulcers or erosions (shallow depressions in the stomach lining). Sucralfate may be useful in preventing gastritis (stomach inflammation) caused by ulcerogenic drugs (such as aspirin). Another use is in the management of acid reflux disease to reduce injury to the esophagus. Sucralfate is also used for the treatment of gastroesophageal reflux disease (GERD) and stress ulcers. Unlike the other classes of medications used for treatment of peptic ulcers, sucralfate is a sucrose sulfate-aluminium complex that binds to the mucosa, thus creating a physical barrier that impairs diffusion of hydrochloric acid in the gastrointestinal tract and prevents degradation of mucus by acid. It also stimulates bicarbonate output and acts like an acid buffer with cytoprotective properties.
The only FDA-approved indication for sucralfate is for the treatment of active duodenal ulcers not related to NSAID usage because the mechanism behind these ulcers is secondary to acid oversecretion. It is not technically approved for gastric ulcers because the main mechanism is not due to acid oversecretion but rather from diminished protection. The use for sucralfate in peptic ulcer disease has diminished recently, but it is still the preferred agent for stress ulcer prophylaxis.
Product name:Sucralfate
CAS Number: 54182-58-0
Molecular formula: C12H54Al16O75S8
Molecular weight:2086.75 g/mol

Information about Nicotinamide Riboside

Nicotinamide Riboside is a natural ingredient that is found in milk. It is actually related to niacin and other forms of vitamin B3. This molecule has become more and more popular today because of various scientific studies that prove its ability to prevent obesity by helping you fight weight gain. Researchers have found that this molecule can serve as a unique supplement that will boost one’s metabolism to help burn off more calories and prevent weight gain. Apart from preventing weight gain, it also helps boost muscle performance, increase energy expenditure, and minimize the risk factors of diabetes. What makes this milk ingredient even more appealing is that it does not have any side effects.
Basically, Nicotinamide Riboside is a naturally occurring precursor of NAD+. What NAD does it is allows sugars, proteins, and fats to be converted into energy. Thus, this process simply shows that nicotinamide riboside boosts NAD levels in the cells of mammals to burn sugars, proteins, and fats as energy to encourage weight loss. In order to further study the many health benefits of nicotinamide riboside (NR), Dr. Suave invented a straightforward methodology to synthesize NR so that it could be studied on a much larger scale. This method of synthezization is patented by Cornell’s Center for Technology Enterprise and Commercialization and is licensed to ChromaDex Corportation.

what is Montelukast sodium ?

Montelukast sodium  is a potent, selective, anti-inflammatory CysLT1 receptor antagonist (IC50 < 5nM) with no appreciable affect on the CysLT2 receptor. In rat colitis Montelukast Sodium has demonstrated the ability to increase PGE2 (Prostaglandin E2 - sc-201225) production and lower COX-2 expression. Inhibition is competitive with respect to leukotrienes - particularly LTD4, a biologically active mediator that plays an important role in the control of several biochemical pathways involving pulmonary and immune system function.
CAS:151767-02-1
Molecular Formula:C35H35ClNNaO3S
Molecular Weight:608.17
Specifications: Montelukast sodium Specifications can be made available on request
Product Description: Montelukast sodium is a selective and orally active leukotriene receptor antagonist that inhibits the cysteinyl leukotriene CysLT1 receptor.

what is Pilocarpine Hydrochloride ?

Pilocarpine Hydrochloride is a parasympathomimetic alkaloid obtained from the leaves of tropical American shrubs from the genus Pilocarpus. It is a non-selective muscarinic receptor agonist in the parasympathetic nervous system, which acts therapeutically at the muscarinic acetylcholine receptor M3 due to its topical application, e.g., in glaucoma and xerostomia.
Pilocarpine has been used in the treatment of chronic open-angle glaucoma and acute angle-closure glaucoma for over 100 years. It acts on a subtype of muscarinic receptor (M3) found on the iris sphincter muscle, causing the muscle to contract and engage in miosis. Pilocarpine Hydrochloride  also acts on the ciliary muscle and causes it to contract. When the ciliary muscle contracts, it opens the trabecular meshwork through increased tension on the scleral spur. This action facilitates the rate that aqueous humor leaves the eye to decrease intraocular pressure.
In ophthalmology, pilocarpine is also used to reduce the possibility of glare at night from lights when the patient has undergone implantation of phakic intraocular lenses; the use of pilocarpine would reduce the size of the pupils, relieving these symptoms. The most common concentration for this use is pilocarpine 1%, the weakest concentration.

About Nandrolone Decanoate

Nandrolone Decanoate is a powerful anabolic steroid of the 19-nor class that can provide although slow yet phenomenal results. Without question it is one of the most popular steroidal compounds of all time but at the same time it is also one of the most feared for a largely very ridiculous reason as we will see. By its nature Nandrolone Decanoate is in many ways the perfect bulking steroid as the gains although slow are steady and easily maintainable. However, many will find a solid use for this steroid in a cutting cycle as well, however, by its primary mode of action bulking is where most will find it truly shines.
Unfortunately, like many anabolic steroids Nandrolone Decanoate is largely misunderstood; not only by the general anti-steroid population but by many who are supporters of anabolic steroid use as well. This is evident by the mass of inaccurate and sometimes downright idiotic information passed on from one guy to the next be it at the gym or on the host of related internet message boards. A lot of this misinformation is based on one simple fact; the information regarding anabolic androgenic steroids is not as vast as many other subjects due to the nature of the topic. However, quality information does exist, the truth does exist and to find it sometimes you have to do a little digging.
Catalog No: 3B3-004745
CAS No: 360-70-3
Molecular Formula: C28H44O3
Molecular Weight: 428.65

What is Finasteride ?

Finasteride is a drug that belongs to the class of androgen inhibitors, which means that it blocks the production of male sex hormones. Finasteride has two main purposes: the treatment of urinary problems in men caused by benign prostatic hypertrophy (BPH) or enlargement of the prostate gland; and the stimulation of new hair growth in men with male pattern baldness. Finasteride was first approved by the Food and Drug Administration (FDA) in 1992 under the trade name Proscar as a treatment for BPH. It received a second FDA approval in December 1997 under the trade name Propecia for the treatment of hair loss in men. Finasteride has also been used by some European doctors to treat hair loss in postmenopausal women, although its use in women is considered controversial in the United States. It is considered the most effective nonsurgical treatment for male pattern baldness as of 2005.
Finasteride works to relieve such symptoms of prostate enlargement as urinary urgency, the need to urinate frequently at night (nocturia), inability to completely empty the bladder, incontinence, or painful urination (dysuria) by blocking the production of DHT. DHT causes the prostate gland to grow and increase pressure on the bladder. As the swollen prostate gradually shrinks, the patient finds it easier to pass urine without discomfort and to empty the bladder completely before going to sleep. Some doctors also prescribe finasteride as pretreatment for prostate surgery, as it lowers the risk of severe bleeding during the operation.Finasteride should be stored in dry places and should be kept at a temperature between 59°F and 86°F (15-30°C). Heat and moisture may cause the drug to lose its potency.
The drug can be safely handled by pregnant women as long as the tablets are intact; however, crushed or broken tablets should not be touched by a pregnant woman as the drug can be absorbed through the skin. If the woman is carrying a male fetus, the drug can cause abnormalities in the baby's sex organs. The FDA issued a warning in 2003 that men taking finasteride should not donate blood until one month after the final dose of the drug, on the grounds that their blood could contain high enough levels of the medication to cause birth defects in a male baby if given to a pregnant woman.
Patients should be advised that finasteride takes several months to reach its full effect—as long as six months for BPH and three months for hair regrowth. In addition, the drug's effects on the body are not permanent; the prostate will start to enlarge again or the hair growth will be lost if the patient stops taking the drug.

what is Minoxidil ?

Minoxidil is an antihypertensive vasodilator medication. It also slows or stops hair loss and promotes hair regrowth. Now off-patent, it is available over-the-counter for the treatment of androgenic alopecia. Widely used for the treatment of hair loss, it has been proven clinically effective in both the prevention of loss and in establishing varying degrees of hair re-growth in males and females suffering pattern baldness. Minoxidil must be used indefinitely for continued support of existing hair follicles and the maintenance of any experienced hair regrowth.Minoxidil needs to be applied once or the recommended twice daily, and may be used indefinitely for continued support of existing hair follicles and the maintenance of any experienced hair regrowth. To achieve maximum effect, the solution should be in contact with the scalp for at least 4 hours before allowing hair to get wet. Minoxidil stimulates hair follicles and growth, but does not reduce DHT or the enzyme responsible for its accumulation around the hair follicle, 5-alpha reductase, which is the primary mediator of male pattern baldness in genetically susceptible individuals. Therefore, when treatment is stopped, the DHT has its expected effect of shrinking and ultimately destroying the genetically predisposed hair follicles.

Information about Baclofen

Baclofen  is a derivative of gamma-aminobutyric acid (GABA). It is primarily used to treat spasticity and is in the early research stages for use for the treatment of alcoholism. It is also used by compounding pharmacies in topical pain creams as a muscle relaxant.
It is an agonist for the GABAB receptors. Its beneficial effects in spasticity result from actions at spinal and supraspinal sites. Baclofen can also be used to treat hiccups, and has been shown to prevent rises in body temperature induced by the drug MDMA in rats.
In addition, research has shown baclofen to be effective in the treatment of alcohol dependence and withdrawal, by inhibiting both withdrawal symptoms and cravings.
Similarly, baclofen assists with a number of the symptoms of opiate withdrawal including muscle cramps and muscle pain as well as the intense shivering often experienced. It may also reduce the general sense of dysphoria and allow some respite from the worst of the symptoms.
A beneficial property of Baclofen  is that tolerance does not seem to occur to a significant degree — baclofen retains its therapeutic anti-spasmodic effects even after many years of continued use. Newer studies, however, indicate that tolerance may develop in some patients receiving intrathecal baclofen treatment.
Baclofen is primarily used for the treatment of spastic movement disorders, especially in instances of spinal cord injury, cerebral palsy, and multiple sclerosis.Its use in people with stroke or Parkinson disease is not recommended.Baclofen produces its effects by activating the GABAB receptor, similar to the drug GHB which also activates this receptor and shares some of its effects. However, baclofen does not have significant affinity for the GHB receptor, and has no known abuse potential The modulation of the GABAB receptor is what produces baclofen's range of therapeutic properties.Baclofen is a white (or off white) mostly odorless crystalline powder, with a molecular weight of 213.66 g/mol. It is slightly soluble in water, very slightly soluble in methanol, and insoluble in chloroform.

what is Trimebutine ?

Trimebutine is a drug with antimuscarinic and weak mu opioid agonist effects.The maleic acid salt of trimebutine is marketed under the trademark of Debridat, Recutin, Polybutin, or Modulon for treatment of irritable bowel syndrome and other gastrointestinal disorders. The major product from drug metabolism of trimebutine in human beings is nor-trimebutine, which comes from removal of one of the methyl groups attached to nitrogen. Trimebutine exerts its effects in part due to causing a premature activation of phase III of the migrating motor complex in the digestive tract. Both Trimebutine and its metabolite are commercially available.
CAS:39133-31-8
Specification:98%
Molecular Formula:C22H29NO5
Formula Weight:387.47g/mol

Information about Pleconaril

Pleconaril is an antiviral drug being developed by Schering-Plough for prevention of asthma exacerbations and common cold symptoms in asthmatic subjects exposed to picornavirus respiratory infections.Although the formulation used by Schering-Plough is a nasal spray, pleconaril is orally bioavailable, and is active against viruses in the Picornaviridae family, including Enterovirus and Rhinovirus.
Pleconaril was originally developed by Sanofi-Aventis, and licensed to ViroPharma in 1997. ViroPharma developed it further, and submitted a New Drug Application to the United States Food and Drug Administration (FDA) in 2001. The application was rejected, citing safety concerns; and ViroPharma re-licensed it to Schering-Plough in 2003. The Phase II clinical trial was completed in 2007. A pleconaril intranasal spray had reached phase II clinical trial for the treatment of the common cold symptoms and asthma complications. However, the results have yet to be reported.
Pleconaril in enteroviruses, prevents the virus from exposing its RNA, and in rhinoviruses prevents the virus from attaching itself to the host cell. Human rhinoviruses (HRVs) contain four structural proteins labeled VP1-VP4. Proteins VP1,VP2 and VP3 are eight stranded anti-parallel β-barrels. VP4 is an extended polypeptide chain on the viral capsid inner surface. Pleconaril binds to a hydrophobic pocket in the VP1 protein. Pleconaril has been shown in viral assembly to associate with viral particles. Through noncovalent, hydrophobic interactions compounds can bind to the hydrophobic pocket. Amino acids in positions Tyr152 and Val191 are a part of the VP1 drug binding pocket.
CAS No.:153168-05-9
Molecular Formula:  C18H18F3N3O3
Molecular Weight:  381.35 g/mol

what is Trimebutine

Trimebutine is a drug with antimuscarinic and weak mu opioid agonist effects.The maleic acid salt of trimebutine is marketed under the trademark of Debridat, Recutin, Polybutin, or Modulon for treatment of irritable bowel syndrome and other gastrointestinal disorders. The major product from drug metabolism of trimebutine in human beings is nor-trimebutine, which comes from removal of one of the methyl groups attached to nitrogen. Trimebutine exerts its effects in part due to causing a premature activation of phase III of the migrating motor complex in the digestive tract. Both Trimebutine and its metabolite are commercially available.
CAS:39133-31-8
Specification:98%
Molecular Formula:C22H29NO5
Formula Weight:387.47g/mol

About Serotonin or 5-hydroxytryptamine

Serotonin or 5-hydroxytryptamine (5-HT) is a monoamine neurotransmitter. Biochemically derived from tryptophan, serotonin is primarily found in the gastrointestinal (GI) tract, platelets, and in the central nervous system (CNS) of animals, including humans. It is popularly thought to be a contributor to feelings of well-being and happiness.
Approximately 90% of the human body's total serotonin is located in the enterochromaffin cells in the alimentary canal (gut), where it is used to regulate intestinal movements. The remainder is synthesized in serotonergic neurons of the CNS, where it has various functions. These include the regulation of mood, appetite, and sleep. Serotonin also has some cognitive functions, including memory and learning. Modulation of serotonin at synapses is thought to be a major action of several classes of pharmacological antidepressants.
Serotonin secreted from the enterochromaffin cells eventually finds its way out of tissues into the blood. There, it is actively taken up by blood platelets, which store it. When the platelets bind to a clot, they release serotonin, where it serves as a vasoconstrictor and helps to regulate hemostasis and blood clotting. Serotonin also is a growth factor for some types of cells, which may give it a role in wound healing.Serotonin is a neurotransmitter and is found in all bilateral animals, where it mediates gut movements and the animal's perceptions of resource availability. In less complex animals, such as invertebrates, resources simply mean food availability. In more complex animals, such as arthropods and vertebrates, resources also can mean social dominance. In response to the perceived abundance or scarcity of resources, an animal's growth, reproduction or mood may be elevated or lowered. This may somewhat depend on how much serotonin the organism has at its disposal.

what is Lufenuron ?

Lufenuron, a benzoylurea pesticide, inhibits the production of chitin in larval fleas. Without chitin, a larval flea will never develop an exoskeleton. Attacking the ability to create chitin may make lufenuron a remedy against fungal infections, such as ringworm (a dermatophyte infection and not a worm at all).It has no known toxic effects at any dosage on humans or other animals in the environment that do not depend on chitin, though the orally-administered pills can sometimes cause an upset stomach with acid reflux.
Lufenuron is thought to be an effective antifungal in plants. It is safe because it is biochemically inert to mammals. Lufenuron is not broken down by the liver or kidneys. Its antifungal property may be due to inhibition of chitin synthesis, which makes up roughly 33% of the typical fungal cell wall.
CAS:103055-07-8

Molecular Formula:C17H8Cl2F8N2O3

Molecular Weight:511.15g/mol

About Donepezil Hydrochloride

Donepezil is used to ease the symptoms of dementia associated with Alzheimer's disease, such as memory loss.
Donepezil cannot cure dementia, but it can slow down the progression of the symptoms in some people. It works by increasing the level of a natural chemical called acetylcholine. This is a chemical which allows nerve cells in the brain to communicate with each other, and it is known that people with dementia have low levels of it.
Donepezil will be prescribed by a doctor who is a specialist. If you are a caregiver, please read this leaflet on behalf of the person who is receiving donepezil.:Donepezil hydrochloride specifications available on request, FORM I & III available.
Donepezil Hydrochloride was the first piperidine-type reversible cholinesterase (ChE) inhibitor to receive approval by the FDA. Donepezil Hydrochloride is approved for the symptomatic management of mild to severe Alzheimer's disease.
CAS:120011-70-3
Molecular Formula:C24H29NO3.HCl
Molecular Weight:415.95

Information about Pleconaril

Pleconaril is an antiviral drug being developed by Schering-Plough for prevention of asthma exacerbations and common cold symptoms in asthmatic subjects exposed to picornavirus respiratory infections.Although the formulation used by Schering-Plough is a nasal spray, pleconaril is orally bioavailable, and is active against viruses in the Picornaviridae family, including Enterovirus and Rhinovirus.
Pleconaril was originally developed by Sanofi-Aventis, and licensed to ViroPharma in 1997. ViroPharma developed it further, and submitted a New Drug Application to the United States Food and Drug Administration (FDA) in 2001. The application was rejected, citing safety concerns; and ViroPharma re-licensed it to Schering-Plough in 2003. The Phase II clinical trial was completed in 2007.[1] A pleconaril intranasal spray had reached phase II clinical trial for the treatment of the common cold symptoms and asthma complications. However, the results have yet to be reported.

CAS No.:153168-05-9
Molecular Formula:  C18H18F3N3O3
Molecular Weight:  381.35 g/mol

About Serotonin or 5-hydroxytryptamine (5-HT)

Serotonin or 5-hydroxytryptamine (5-HT) is a monoamine neurotransmitter. Biochemically derived from tryptophan, serotonin is primarily found in the gastrointestinal (GI) tract, platelets, and in the central nervous system (CNS) of animals, including humans. It is popularly thought to be a contributor to feelings of well-being and happiness.
Approximately 90% of the human body's total serotonin is located in the enterochromaffin cells in the alimentary canal (gut), where it is used to regulate intestinal movements. The remainder is synthesized in serotonergic neurons of the CNS, where it has various functions. These include the regulation of mood, appetite, and sleep. Serotonin also has some cognitive functions, including memory and learning. Modulation of serotonin at synapses is thought to be a major action of several classes of pharmacological antidepressants.
Serotonin secreted from the enterochromaffin cells eventually finds its way out of tissues into the blood. There, it is actively taken up by blood platelets, which store it. When the platelets bind to a clot, they release serotonin, where it serves as a vasoconstrictor and helps to regulate hemostasis and blood clotting. Serotonin also is a growth factor for some types of cells, which may give it a role in wound healing.Serotonin is a neurotransmitter and is found in all bilateral animals, where it mediates gut movements and the animal's perceptions of resource availability. In less complex animals, such as invertebrates, resources simply mean food availability. In more complex animals, such as arthropods and vertebrates, resources also can mean social dominance. In response to the perceived abundance or scarcity of resources, an animal's growth, reproduction or mood may be elevated or lowered. This may somewhat depend on how much serotonin the organism has at its disposal.
Serotonin or 5-hydroxytryptamine (5-HT) is widely applied in pharmaceutical, food, health care and other industries.

About Chromium polynicotinate

Chromium polynicotinate is a picolinic acid bounded with chromium. It is more effective than any other type of chromium bounded acid, as it binds the elemental chromium to niacin. This is more absorbable in the body. In pharmaceutic industry, it is used as drug intermediate.
Chromium polynicotinate is an ionic substance used in some nutritional supplement products. It appears in products that are referred to as a medical food used for nutritional support for conditions associated with diabetes mellitus type 2. The product is also known as niacin-bound chromium, as referred to in an article about Hydroxycut published by the Department of Physiology and Biophysics of the Georgetown University.
Buy Chromium polynicotinate 

About Biotin

Biotin, also known as vitamin H, it actually belongs to vitamin B, is also an important nutrients essential.
Biotin could act as a cofactor in many enzyme The new supersedes the old. process, involved in carbohydrate, lipid, protein and nucleic acid metabolism, and play an important role. For example, biotin can convert food into energy: can make the cell regeneration, the prevention of gray hair and hair loss, hair and nail health protection: relieve muscle pain; relieve symptoms of dermatitis; improve blood glucose in diabetic patients.
If the body lack of biotin, the skin will appear dry, or even chapped, limbs squamous dermatitis, muscle pain, loss of hair or hair, loss of appetite, nausea, vomiting, red blood cell levels, cholesterol lipid metabolism disorder, depression, increased, insomnia, irritability or indifferent, frustrated and a series of symptoms.
Biotin widely exists in all kinds of animals and plants, food, also can by the human gastrointestinal tract bacterial synthesis. Milk, fruit, beer yeast, soybean meal, peanut, butter, animal offal, lean meat, egg yolk, brown rice, wheat are good sources of biotin. Intake of sulfa drugs, estrogen, alcohol, will absorb the influence of biological. Gastric acid secretion deficiency can also reduce the absorption of biotin, caused by biotin deficiency.
The doctor suggested, drinking or taking antibiotics and sulfa drug people every day should be added a certain amount of biotin; often hair loss, hair thinning people can be adequate intake of biotin. In addition, biotin was lost during pregnancy, should be added the reasonable under the guidance of a doctor or dietitian. Biotin have synergistic effect and vitamin A, B2, B6, niacin, taken together is better.

What is Ceftazidime ?

Ceftazidime is usually reserved for the treatment of infections caused by Pseudomonas aeruginosa. It is also used in the empirical therapy of febrile neutropenia, in combination with other antibiotics. It is usually given IV or IM every 8–12 hours (2 - 3 times a day), with dosage varying by the indication, infection severity, and/or renal function of the recipient.
Ceftazidime  is a third-generation cephalosporin antibiotic. Like other third-generation cephalosporins, it has broad spectrum activity against Gram-positive and Gram-negative bacteria. Unlike most third-generation agents, it is active against Pseudomonas aeruginosa, however it has weaker activity against Gram-positive microorganisms and is not used for such infections.
Ceftazidine is first line treatment for the rare tropical infection, melioidosis.
In addition to the syn-configuration of the imino side chain, compared to other third-generation cephalosporins, the more complex moiety (containing two methyl and a carboxylic acid group) confers extra stability to β-lactamase enzymes produced by many Gram-negative bacteria. The extra stability to β-lactamases increases the activity of ceftazidime against otherwise resistant Gram-negative organisms including Pseudomonas aeruginosa. The charged pyridinium moiety increases water-solubility.

CAS:72558-82-8
Molecular formula:C22H22N6O7S2
Molecular weight:546.58

What is Trimebutine ?

Trimebutine is a drug with antimuscarinic and weak mu opioid agonist effects.The maleic acid salt of trimebutine is marketed under the trademark of Debridat, Recutin, Polybutin or Modulon for treatment of irritable bowel syndrome and other gastrointestinal disorders. The major product from drug metabolism of trimebutine in human beings is nor-trimebutine, which comes from removal of one of the methyl groups attached to nitrogen. Trimebutine exerts its effects in part due to causing a premature activation of phase III of the migrating motor complex in the digestive tract. Both Trimebutine and its metabolite are commercially available.

CAS:39133-31-8
Specification:98%
Molecular Formula:C22H29NO5
Formula Weight:387.47g/mol
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About Sodium Fusidate

Sodium Fusidate (soh-dee-um few-sid-ate) is a medicine which is used in bacterial skin infections.
The information in this Medicine Guide for Sodium Fusidate varies according to the condition being treated and the particular preparation used.Sodium Fusidate is used to treat skin infections such as impetigo, infected eczema or infected wounds or cuts. It works by killing the organisms that have caused the infection
Sodium Fusidate is also used for Osteomyelitis (an infection of the joints and bones) and other infections caused by similar bacteria .Sodium fusidate is used to treat bacterial infections of the joints and bones by killing or stopping the growth of the bacteria responsible.
CAS No.:751-94-0
Synonyms: Fusidic acid sodium salt; 16-(Acetyloxy)-3,11-dihydroxy-29-nordammara-17(20),24-dien-21-oic acid sodium salt
Molecular Formula:  C31H47NaO6
Molecular Weight:  538.70
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What is the Betamethasone ?

Betamethasone is a topical steroid. It reduces or inhibits the actions of chemicals in the body that cause inflammation, redness, and swelling. Betamethasone topical is used to treat inflammation caused by a number of conditions such as allergic reactions, eczema, and psoriasis. Betamethasone is in a class of drugs called steroids. Betamethasone reduces swelling and decreases the body's immune response.Betamethasone is used to treat many different conditions. It is used to treat endocrine (hormonal) disorders when the body does not produce enough of its own steroids. It is also used to treat many immune and allergic disorders, such as arthritis, lupus, psoriasis, asthma, ulcerative colitis, and Crohn's disease.Betamethasone is a synthetic corticosteroid and is used to decrease inflammation. Betamethasone also decreases the numbers of white blood cells circulating in the blood.
Molecular Formula:C22H29FO5
Molecular weight:392.461
CAS NO:378-44-9

What is Vitamin D3 ?

Cholecalciferol (also known as toxiferol) is a form of vitamin D, also called vitamin D3. Vitamin D3 is vitamins drug mainly promote absorption and deposition of calcium and phosphorus in intestines.It is used to treat rickets and osteomalacia,etc.
It is structurally similar to steroids such as testosterone, cholesterol, and cortisol (though vitamin D3 itself is a secosteroid).Cholecalciferol is produced industrially for use in vitamin supplements and to fortify foods by the ultraviolet irradiation of 7-dehydrocholesterol extracted from lanolin found in sheep's wool. Paraphrasing a more detailed explanation, cholesterol is extracted from wool grease and wool wax alcohols obtained from the cleaning of wool after shearing. The cholesterol undergoes a four step process to make 7-dehydrocholesterol, the same compound that is stored in the skin of animals.

7-Dehydrocholesterol is the precursor of vitamin D3. Within the epidermal layer of skin, 7-Dehydrocholesterol undergoes an electrocyclic reaction as a result of UVB radiation, resulting in the opening of the vitamin precursor B-ring through a conrotatory pathway. Following this, the previtamin D3 undergoes a antarafacial sigmatropic rearrangement  and therein finally isomerizes to form vitamin D3.
Cholecalciferol is then hydroxylated in the liver to become calcifediol (25-hydroxyvitamin D3).
Next, calcifediol is again hydroxylated, this time in the kidney, and becomes calcitriol (1,25-dihydroxyvitamin D3). Calcitriol is the most active hormone form of vitamin D3.

CAS:67-97-0
Molecular Formula: C27H44O
Molecular Weight: 384.64 g/mol

About Hyaluronic acid

Hyaluronan (also called hyaluronic acid or hyaluronate) is an anionic, nonsulfated glycosaminoglycan distributed widely throughout connective, epithelial, and neural tissues. It is unique among glycosaminoglycans in that it is nonsulfated, forms in the plasma membrane instead of the Golgi, and can be very large, with its molecular weight often reaching the millions.One of the chief components of the extracellular matrix, hyaluronan contributes significantly to cell proliferation and migration, and may also be involved in the progression of some malignant tumors.

Hyaluronan has been used in attempts to treat osteoarthritis of the knee via injecting it into the joint. It has not been proven, however, to generate significant benefit and has potentially severe adverse effects.
Dry, scaly skin (xerosis) such as that caused by atopic dermatitis (eczema) may be treated with a prescription skin lotion containing sodium hyaluronate as its active ingredient.
In some cancers, hyaluronan levels correlate well with malignancy and poor prognosis. Hyaluronan is, thus, often used as a tumor marker for prostate and breast cancer. It may also be used to monitor the progression of the disease.
Hyaluronan may also be used postoperatively to induce tissue healing, notably after cataract surgery.[11] Current models of wound healing propose the larger polymers of hyaluronic acid appear in the early stages of healing to physically make room for white blood cells, which mediate the immune response.
CAS:     9004-61-9
Molecular Formula:C14H22NNaO11
Formula Weight:403.31
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