Montelukast sodium

Montelukast sodium  is a potent, selective, anti-inflammatory CysLT₁ receptor antagonist (IC₅₀ < 5nM) with no appreciable affect on the CysLT₂ receptor. In rat colitis Montelukast Sodium has demonstrated the ability to increase PGE2 (Prostaglandin E2 - sc-201225) production and lower COX-2 expression. Inhibition is competitive with respect to leukotrienes - particularly LTD4, a biologically active mediator that plays an important role in the control of several biochemical pathways involving pulmonary and immune system function.

CAS:151767-02-1
Molecular Formula:C35H35ClNNaO3S
Molecular Weight:608.17
Specifications:Montelukast sodium Specifications can be made available on request
Product Description: Montelukast sodium is a selective and orally active leukotriene receptor antagonist that inhibits the cysteinyl leukotriene CysLT1 receptor.