The characteristics of Propyzamide

Occurrence of propyzamide residues in rotational crops was advised during the associate analysis of propyzamide. In adjustment to abstain propyzamide residues in rotational crops it is recommended that the Member States afore acceding an approval for the use of propyzamide should accede the charge for establishing bulb aback intervals for rotational crops that accept abbreviate frondescence periods.The toxicological contour of propyzamide was evaluated in the framework of Directive 91/414/EEC, which resulted in an ADI of 0.02 mg/kg bw/d. An ARfD was not accounted necessary.
Primary crop metabolism of propyzamide was advised afterward foliar appliance in lettuce, alfalfa and winter rape, which alone covers two groups of crops (leafy crops and pulses & oilseeds).
Metabolic patterns in those altered studies were apparent to be similar. Since propyzamide is mainly activated during aboriginal advance stages of the crop or during cessation (soil applications), rotational crop studies (carrot, bill and wheat) accept been be taken into annual to complete the appraisal of the metabolic alleyway of propyzamide. It was assured that the arrangement of metabolites is commensurable with the metabolites empiric in primary crops. Hence, the accordant balance for administration and accident appraisal in all crops accurate in the framework of this analysis was authentic as ancestor propyzamide. A accurate analytic adjustment for administration of this balance analogue with a LOQ of 0.01 mg/kg in all bulb bolt is available.Propyzamide was included in Annex I to Directive 91/414/EEC on 01 April 2004, which is afore the access into force of Adjustment (EC) No 396/2005 on 02 September 2008. EFSA is accordingly appropriate to accommodate a articular assessment on the analysis of the absolute MRLs for that alive actuality in acquiescence with Article 12(2) of afore mentioned regulation. In adjustment to aggregate the accordant pesticide residues data, EFSA asked Sweden, as the appointed rapporteur Member State (RMS), to complete the Pesticide Residues Overview File (PROFile).
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