About Desmopressin

Desmopressin  is a synthetic replacement for vasopressin, the hormone that reduces urine production. It may be taken nasally, intravenously, or as an oral or sublingual tablet. Physicians prescribe desmopressin most frequently for treatment of diabetes insipidus, bedwetting, or nocturia.

Doctors prescribe desmopressin frequently for treatment. It is usually in the form of desmopressin acetate, DDAVP. Patients taking DDAVP are 4.5 times more likely to sleep without disruption than with placebo. [1] [2] Examples of these situations are overnight camp and sleepovers.
US drug regulators banned treating bedwetting with Desmopressin nasal sprays after two patients died and 59 other patients suffered seizures. The patients were using desmopressin when they developed hyponatremia, an imbalance of the body's sodium levels.
FDA regulators said that desmopressin tablets could still be considered safe for nocturnal enuresis treatment, as long as the patient was otherwise healthy. Patients must stop taking desmopressin if they become sick and have severe vomiting and diarrhea, fever, the flu, or severe cold. They should also be very cautious during hot weather or following strenuous exercise that may make them thirsty.
CAS NO:16789-98-3

Molecular formula:C₄₆H₆₄N₁₄O₁₂S₂

Molecular weight: 1069.24

Appearance:White powder

Purity(by HPLC):  ≥98.00%～99.90%

Amino Acid Composition: ±10% of theoretical

Water Content(Karl Fischer): ≤4.80%

Acetate Content(HPIC):≤6.80%
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